Pernicious Anemia Cascade

Test Code

ACASM

Specimen Name

Pernicious Anemia Cascade

CPT Codes

  • 82607

Collect

SST-Serum

Stability

30 days frozen

Volume

3 mLs

Minimum Volume

1.6 mLs

Performed

Performed Monday through Saturday - 1-5 days

Components

Includes: Vitamin B12 Assay, S; Gastrin, S; Intrinsic Factor Blocking Ab, S; Methylmalonic Acid, QN, S

Additional Information

Patient Preparation: Ask patients if they have received a vitamin B12 injection or radiolabeled vitamin B12 injection within the last 2 weeks. Patient results will not reflect deficiency or malabsorption after recent B12 injection. If patient has received such an injection within the past 2 weeks, this test should not be ordered. https://www.mayocliniclabs.com/-/media/it-mmfiles/Special-Instructions/A/6/3/benign-hematology-test-request-form. Patient Preparation: 1. Fasting: 12 hours, required 2. For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7). 3. For 1 week before specimen collection, if medically feasible, patient should not take proton pump inhibitors (omeprazole, lansoprazole, dexlansoprazole, esomeprazole, pantoprazole, and rabeprazole). 4. For at least 2 weeks before specimen collection, patient should not take or receive drugs that interfere with gastrointestinal motility (eg, opioids).

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Common Lab Definitions

  • Serum 
  • Plasma 
  • STT