ANA, IgG by ELISA w/reflex to ANA, HEp2 Substrate

Specimen:

Test Code

ANAH2G

Specimen Name

ANA, IgG by ELISA w/reflex to ANA, HEp2 Substrate

Collect

1-SST

Submit

1 mL (Min: 0.5 mL) Serum Refrigerated

Special Handling

Separate serum from cells ASAP or within 2 hours of collection.

Rejection Criteria

Non-serum, heat inactivated, grossly hemolyzed, or severely lipemic specimens.

Stability

Ambient 48 hours; Refrigerated 14 days; Frozen 1 year (avoid repeated freeze/thaw cycles)

Methodology

Qualitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody

Performed

Sunday - Saturday

Reported

2-5 days

CPT Codes

  • 86038
  • if reflexed
  • add 86039

Components

If ANA are detected by ELISA, then Antinuclear Antibody (ANA), HEp-2, IgG by IFA will be added.

Additional Information

ANA identified by indirect fluorescence assay (IFA) using HEp-2 substrate and IgG-specific conjugate at a screening dilution of 1:80. Positive nuclear patterns reported include homogeneous, speckled, centromere, nucleolar, or nuclear dots. Positive cytoplasmic patterns reported include reticular/AMA, discrete/GW body-like, polar/golgi-like, rods and rings, or cytoplasmic speckled patterns. All positive results are reported with endpoint titers at no additional charge.

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Common Lab Definitions

  • Serum 
  • Plasma 
  • STT