TMAO (Trimethylamine N-oxide)

Specimen:

Test Code

TMAO

Specimen Name

TMAO (Trimethylamine N-oxide)

Collect

1-Plain Red Top Also acceptable EDTA

Submit

1 mL (Min: 0.5 mL) Serum or Plasma

Special Handling

For specimens collected in plain red-top tube, hold tube upright at room temperature for 45 minutes and allow to clot. Centrifuge specimen after clotting according to manufacturer's specifications. Transfer to a transport tube for storage at (2°C to 8°C) until shipped. Plasma must be separated from cells within 45 minutes of venipuncture. Send plasma in a plastic transfer tube.

Rejection Criteria

Serum specimen drawn in gel-barrier collection tube other than the NMR LipoTube; sample older than 14 days

Stability

Preferred/Transport Refrigerated 14 days; Ambient 14 days; Frozen 14 days

Methodology

Nuclear magnetic resonance (NMR)

Performed

Reported

4-7 days

CPT Codes

  • 84999

Components

Additional Information

TMAO levels are lower in humans who follow a vegetarian or vegan diet than in omnivores. Because TMA and TMAO are naturally abundant in some fish, patients should fast overnight and refrain from consuming fish and other marine food items the day before the blood draw. Fasting for 10 to 12 hours is recommended.

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Common Lab Definitions

  • Serum 
  • Plasma 
  • STT