- YCDQDNAR
Celiac HLA DQ2, DQ8
Specimen:
Test Code
YCDQDNAR
Specimen Name
Celiac HLA DQ2, DQ8
Collect
Yellow Top ACD Whole Blood OR EDTA Whole Blood
Submit
10 mLs ACD Whole Blood or 5 mLs (Min. 1 mL) EDTA (Lavender) Whole Blood, Ambient or Refrigerated
Special Handling
Mix tubes thoroughly immediately upon collection. For pediatric collection: 0.5 mL EDTA (Lavender) tube, whole blood.
Rejection Criteria
Specimens drawn in Heparin
Stability
Ambient: 7 days; Refrigerated: 7 days
Methodology
DNA amplification and Liquid Bead array detection
Performed
Performed Monday through Friday
Reported
Within one week
CPT Codes
- 81376
Components
—
Additional Information
Only send to PSPC Monday through Thursday and must be received at PSPC (North Platte) the same day as collected. Over 90% of patients with celiac disease express HLA DQ2 and the remainder express DQ8. The HLA DQ2 and DQ8 alleles are associated with increased genetic susceptibility for celiac disease.
The frequency of celiac risk genotypes in the general population is about 30%, whereas only 1 to 3% actually develops disease. Associations of DQ2 and/or DQ8 with irritable bowel syndrome have also been reported.
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Test Information
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Common Lab Definitions
- Serum
- Plasma
- STT