Tissue Transglutaminase (tTG) IgA

Specimen:

Test Code

YTTG

Specimen Name

Tissue Transglutaminase (tTG) IgA

Collect

SST-Serum

Submit

2 mL (Min: 0.5 mL) Serum, Refrigerated.

Special Handling

Allow specimen to clot completely at room temperature. Separate from cells ASAP. If transport to lab is not the same day as collected, aliquot the serum.

Rejection Criteria

Plasma and other body fluids. Heat-inactivated, hemolyzed, lipemic or contaminated specimens.

Stability

After separation from cells: Ambient: <8 hours; Refrigerated: up to 7 days; For longer storage, freeze at -20º Celsius. Avoid multiple freeze/thaw cycles.

Methodology

Mulitplex Flow Immunoassay

Performed

Monday - Friday

Reported

3-5 days

CPT Codes

  • 86364

Components

—

Additional Information

tTG-IgA can be used to monitor adherence to a strict gluten-free diet since IgA levels decline in the absence of gluten. To monitor treatment, the tTG-IgA alone can be retested 6 months after initiation of a gluten-free diet and then monitored annually.

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Common Lab Definitions

  • Serum 
  • Plasma 
  • STT