Olanzapine (Zyprexa)

Specimen:

Test Code

ZYPA

Specimen Name

Olanzapine (Zyprexa)

Collect

1-Plain Red Top Also acceptable EDTA

Submit

2 mL (Min: 1 mL) Serum or Plasma Critical Frozen

Special Handling

Separate serum or plasma from cells within 2 hours of collection. Pour off into a transport tube.

Rejection Criteria

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution). Hemolyzed samples.

Stability

CRITICAL FROZEN 30 days. Ambient: Unacceptable; Refrigerated: Unacceptable

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Tuesday/Friday

Reported

2-8 days

CPT Codes

  • 80342

Components

Additional Information

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Olanzapine shows slight interference with high levels of hemolysis in the sample. Noroxycodone causes an analytical interference and impacts the quantitation of Olanzapine.

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Common Lab Definitions

  • Serum 
  • Plasma 
  • STT